Main Article Content
Benesi-Hildebrand equation, binding constant, polyphenols, ruthenium (II)-polypyridyl complexes, structural effect
The binding of three Ru(II)-polypyridyl complexes with polyphenols (gallic acid and quercetin) have been studied in aqueous medium at pH 11 by means of absorption spectral technique. The absorption and emission maximum of this complexes are in the range of 451-457 nm and 612-626 nm respectively. The binding constant (Kb) for these reactions are determined from the Benesi-Hildebrand equation using absorption intensity data.
The observed binding constant values are sensitive to the nature of the ligand and the structure of the gallic acid and quercetin. Quercetin binds strongly with Ru(II) complexes than gallic acid owing to the presence of more phenolic –OH groups. Structural effect seems to play a vital role on the binding of the antioxidants with these complexes.
Janeiro, P., Novak, I., Seruga, M. Brett, A.M.O., Electroanalytical oxidation of p-coumaric acid, Anal. Lett., (40), 2007, 3309–3321.
Dolatabadi, J.E.N., Mokhtarzadeh, A., Ghareghoran, S.M., Dehghan, G., Synthesis, Characterization and Antioxidant Property of Quercetin-Tb(III) Complex, Advanced Pharmaceutical Bulletin, (4), (2), 2014, 101–104.
Lo, K.K.W., Louie, M.W., Zhang, K.Y., Design of luminescent iridium(III) and rhenium(I) polypyridine complexes as in vitro and in vivo ion, molecular and biological probes, Coord Chem Rev., (254) 2010, 2603–2622
Meggers, E., Targeting proteins with metal complexes, Chem Commun., 2009, 1001–1010
Sheikhshoaie, I., Badiei, A., Ghazizadeh, M., Synthesis and characterization of a new poly (amidoamine) dendrimer-like iron (iii) and molybdenum (VI) complexes, Der Chemica Sinica., (3), (1), 2012, 29 –37.
Sabastiyan, A., Suvaikin, M.Y., Synthesis, characterization and antimicrobial activity of 2-(dimethylaminomethyl)isoindoline-1,3-dione and its cobalt(II) and nickel(II) complexes, Advances in Applied Science Research, (3), (1), 2012, 45–50.
Kostova, I., Momekov, G., New zirconium (IV) complexes of coumarins with cytotoxic activity, Eur. J. Med. Chem., (41), (6), 2006, 717–726.
Rajeshirke, M., Shah, R., Yadav, P., Purohit, N.V., Synthesis and antioxidant activity of metal (II) complexes of isocoumarin derivatives, Der Pharmacia Sinica., (3), (2), 2012, 239–248.
Maksimoska, J., Feng, L., Harms, K., Yi, C., Kissil, J., Marmorstein, R., Meggers, E., Targeting Large Kinase Active Site with Rigid, Bulky Octahedral Ruthenium Complexes, J Am Chem Soc., (130), 2008, 15764–15765.
Babu. E., Mareeswaran, P.M.,, Singaravadivel, S., Bhuvaneswari, J., Rajagopal, S., A selective, long-lived deep-red emissive ruthenium(II) polypyridine complexes for the detection of BSA, Spectrochimica Acta A, (130), 2014, 553–560.
Perron, N.R., Brumaghim, J.L., A review of the antioxidant mechanisms of polyphenol compounds related to iron binding cell, Biochem Biophys., (53), 2009, 75–100.
Farhan, S.A., Study on the interaction of copper (II) complex of morin and its antimicrobial effect, Int. J. Chem. Sci., (11), (3), 2013, 1247–1255.
Thanasekaran, P., Rajendran, T., Rajagopal, S., Srinivasan, C., Ramaraj, R., Ramamurthy, P., Venkatachalapathy, B., Marcus inverted region in the photoinduced electron transfer reactions of ruthenium(II)-polypridyl complexes with phenolate ions, J. Phys. Chem. A, (101), 1997, 8195–8199.
Saha, B., Stanbury, D.M., Thermal and photochemical reduction of aqueous chlorine by ruthenium(II) polypyridyl complexes, Inorg. Chem., (39), 2000, 1294–1300.
Connors, K.A., Binding Constants: The Measurement of Stability, John Wiley & Sons, Ltd, Chichester, U.K, 1987.
Ramešová, S., Sokolová, R., Degano, I., Bulíčková, J., Žabka, J., Gál, M., On the stability of the bioactive flavonoids quercetin and luteolin under oxygen-free conditions, Anal. Bioanal. Chem., (402), 2012, 975–982.
Li, C., Hoffman, M.Z., Oxidation of phenol by singlet oxygen photosensitized by the tris(2,2ˈ bipyridine)ruthenium(II) ion, J. Phys. Chem. A, (104), 2000, 5998–6002.