Color Tuneable Bio-Sensor Made Up From Stimuli-Responsive Nanoparticles

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Aashish Agarwal


sensors, nanotechnology, protein-sensor, stimuli-responsive nanoparticles, Bragg’s law, self-assemble and diffraction,


A biosensor is a device that is made up of transducer and biological elements [1-3]. The biological elements can be proteins, enzymes or antibodies [1]. The biological elements interact with the analyte which convert the biological response to an electrical signal. So usually biosensor consists of a biological component (acting as a sensor) and an electrical component (for detecting and transmitting the signal). Biosensors have a wide range of applications in different areas of science such as health care industry, clinical analysis and diagnosis of disease and agriculture [4]. In particular, there is a growing interest to prepare bio-sensor using different types of nanomaterials such as gold nanoparticles, carbon nanotubes, quantum dots, etc. [4].

In the current proposal, we plan to prepare a low cost protein-sensor using polymeric stimuli-responsive nanoparticles based on diffraction principle. Moreover, this sensor will have a switchable functionality towards pH, temperature and electric field and also can be used with high accuracy of proteins detection based on a simple diffraction principle in the visible region. Since the awareness regarding health and wellbeing is increasing day by day in the global population, the use of biosensors in diagnostics is also simultaneously growing. Thus we believe that our proposed protein sensor based on diffraction principle will also have a popular demand in health care industry. 

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[1] Xinping Zhang, et. al. Sensors 2012, 12, 12082.

[2] Bo Lin et al. Biosensors and Bioelectronics 2002, 17, 827.


[4] Suresh Sagadevan and Mathan Periasamy, Rev. Adv. Mater. Sci. 2014, 36, 62.

[5] Priti S. Mohanty, et. al. Hydrogel Micro- and Nanoparticles” L. A. Lyon and Michael J. Serpe, Eds. WILEY-VCH (2012), ISBN: 9783527330331 (Review Chapter).

[6] Priti S. Mohanty, et. al. The Journal of Chemical Physics 2014, 140, 094901.

[7] Priti S. Mohanty et. al. , Journal of Physical Chemistry (LETTERS) 2008, 112, 14692.

[8] Priti S. Mohanty, et. al. Langmuir, 2009, 25, 194