CENTRAL PONTINE MYELINOLYSIS IN CELIAC DISEASE PATIENT- A CASE REPORT

Main Article Content

Dr. Pushpendra Kumar Patel
Dr. Rishav Raj

Keywords

CENTRAL PONTINE MYELINOLYSIS, CELIAC DISEASE, PATIENT,

Abstract

Central pontinemyelinolysis(CPM)also known as osmotic demyelination syndrome , is a neurological disease caused by severe damage of the myelin sheath of nerve cells in the brainstem, more precisely in the area termed the pons, predominately of iatrogenic etiology1. It is characterized by acute paralysis, dysphagia (difficulty in swallowing), and dysarthria (difficulty inspeaking), and other neurological symptoms.2

The most common cause is the too rapid correction of low blood sodium levels.CPM may also occur in patients affected by

  • Severe liver disease
  • Liver transplant
  • Alcoholism
  • Severe burns
  • Malnutrition
  • Anorexia
  • Severe electrolyte disorders
  • AIDS
  • Hyperemesis gravidarum
  • Hyponatremia due to Peritoneal Dialysis
  • Wernicke encephalopathy
Abstract 76 | PDF Downloads 8

References

1. Gocht A, Colmant HJ (1987). "Central pontine and extrapontinemyelinolysis: a report of 58 cases". Clin. Neuropathol. 6 (6): 262–70. PMID 3322623.

2. Lampl C, Yazdi K (2002). "Central pontinemyelinolysis". Eur. Neurol. 47 (1): 3–10. https://doi.org/10.1159/000047939PMID 11803185. Archived from the original on 2010-11-18.

3. Babar, S. (October 2013). "SIADH Associated With Ciprofloxacin." (PDF). Annals of Pharmacotherapy. Sage Publishing. 47 (10):1359–1363. doi:10.1177/1060028013502457. ISSN 1060-0280. PMID 24259701. Retrieved November 18, 2013.https://doi.org/10.1177/1060028013502457

4. Musana AK, Yale SH (August 2005). "Central pontinemyelinolysis: case series and review". WMJ. 104 (6): 56–60. PMID 16218318.

5. Odier C, Nguyen DK, Panisset M (July 2010). "Central pontine and extrapontinemyelinolysis: from epileptic and other manifestations to cognitive prognosis". J. Neurol. 257 (7): 1176–80. doi:10.1007/s00415-010-5486-7. PMID 20148334.https://doi.org/10.1007/s00415-010-5486-7